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David Malkin Selected Research

Choroid Plexus Neoplasms (Choroid Plexus Tumor)

1/2019Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma.
1/2019DNA methylation signature is prognostic of choroid plexus tumor aggressiveness.
1/2015Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups.
6/2012Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010.

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David Malkin Research Topics

Disease

76Neoplasms (Cancer)
01/2022 - 08/2002
17Medulloblastoma
01/2021 - 10/2008
7Brain Neoplasms (Brain Tumor)
01/2019 - 02/2006
6Rhabdomyosarcoma
12/2009 - 12/2005
5Osteosarcoma (Osteogenic Sarcoma)
10/2019 - 03/2005
4Leukemia
11/2021 - 05/2002
4Choroid Plexus Papilloma
10/2021 - 04/2010
4Carcinogenesis
01/2020 - 08/2002
4Choroid Plexus Neoplasms (Choroid Plexus Tumor)
01/2019 - 06/2012
4Li-Fraumeni Syndrome
01/2017 - 06/2012
4Neuroblastoma
10/2008 - 04/2004
3Glioma (Gliomas)
01/2021 - 01/2011
3Turcot syndrome
01/2021 - 01/2016
3Ewing Sarcoma (Sarcoma, Ewing)
01/2018 - 04/2005
3Sarcoma (Soft Tissue Sarcoma)
11/2017 - 04/2005
3Genetic Predisposition to Disease (Genetic Predisposition)
01/2016 - 01/2006
3Carcinoma (Carcinomatosis)
01/2015 - 01/2003
2Genomic Instability
10/2022 - 06/2016
2Microsatellite Instability
01/2021 - 11/2017
2Adrenocortical Carcinoma
01/2020 - 02/2016
2Choroid Plexus Carcinoma
01/2019 - 01/2019
2Renal Cell Carcinoma (Grawitz Tumor)
05/2017 - 01/2013
2Chromothripsis
06/2016 - 08/2012
2Paraganglioma (Paragangliomas)
02/2016 - 01/2013
2Hemangioblastoma
02/2016 - 10/2005
2Glioblastoma (Glioblastoma Multiforme)
01/2016 - 01/2012
2Hypoxia (Hypoxemia)
07/2008 - 08/2005
2Necrosis
07/2006 - 03/2005
1Chromosomal Instability (Chromosome Stability)
01/2022
1Hematologic Neoplasms (Hematological Malignancy)
11/2021
1Pediatric Adrenocortical Carcinoma
01/2021
1Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
01/2021
1Stomach Neoplasms (Stomach Cancer)
07/2020
1Adenocarcinoma
07/2020
1Typical Teratoid Rhabdoid Tumor
01/2019
1Rhabdoid Tumor (Rhabdoid Tumors)
01/2019
1Cerebellar Neoplasms
05/2016
1Wilms Tumor (Wilm's Tumor)
02/2016
1Pleuropulmonary blastoma
02/2016

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
01/2021 - 04/2005
9DNA (Deoxyribonucleic Acid)IBA
01/2022 - 08/2002
7Biological ProductsIBA
11/2021 - 02/2006
7Biomarkers (Surrogate Marker)IBA
05/2017 - 01/2006
5cytidylyl-(3'-5')-cytidine (CpC)IBA
01/2019 - 04/2010
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2020 - 08/2003
4Telomerase (Telomerase Reverse Transcriptase)IBA
12/2014 - 02/2006
3DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
01/2021 - 03/2015
3Cisplatin (Platino)FDA LinkGeneric
07/2020 - 04/2005
3Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2020 - 12/2005
32- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
01/2019 - 06/2012
3RNA (Ribonucleic Acid)IBA
05/2016 - 02/2012
3integrin-linked kinaseIBA
05/2010 - 06/2009
2hydrogen sulfite (bisulfite)IBA
01/2022 - 10/2016
2NucleotidesIBA
01/2021 - 10/2019
2CarcinogensIBA
01/2020 - 11/2017
26-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA
01/2019 - 01/2015
2Transcription Factors (Transcription Factor)IBA
01/2017 - 01/2014
2MicroRNAs (MicroRNA)IBA
08/2016 - 01/2015
2Antineoplastic Agents (Antineoplastics)IBA
07/2014 - 01/2003
2Formaldehyde (Formol)FDA Link
03/2014 - 04/2012
2ParaffinIBA
03/2014 - 04/2012
2Phosphotransferases (Kinase)IBA
05/2010 - 12/2009
2Insulin-Like PeptidesIBA
05/2010 - 03/2009
2Conditioned Culture MediaIBA
07/2008 - 08/2005
2Doxorubicin (Adriamycin)FDA LinkGeneric
08/2005 - 04/2005
1ChromograninsIBA
10/2022
1Tuberculin (PPD)IBA
01/2022
1Untranslated RNA (Noncoding RNA)IBA
01/2021
1romidepsin (FK228)FDA Link
01/2021
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2021
1Circulating Tumor DNAIBA
12/2020
1Oxaliplatin (Eloxatin)FDA LinkGeneric
07/2020
1RamucirumabIBA
07/2020
1Paclitaxel (Taxol)FDA LinkGeneric
07/2020
1Fluorouracil (Carac)FDA LinkGeneric
07/2020
1Oncogene Proteins (Oncogene Protein)IBA
01/2020
1U1 small nuclear RNAIBA
10/2019
1Glutathione Transferase (Glutathione S-Transferase)IBA
03/2019
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
03/2019
1Lipase (Acid Lipase)FDA Link
10/2018
1RNA-Binding Proteins (RNA-Binding Protein)IBA
01/2018
1Proto-Oncogene Proteins c-etsIBA
01/2018
1MutagensIBA
11/2017
1Genetic Markers (Genetic Marker)IBA
05/2017
1Messenger RNA (mRNA)IBA
05/2016
1arseniteIBA
05/2016
15' Untranslated Regions (5' UTR)IBA
05/2016
1RNA Helicases (RNA Helicase)IBA
05/2016
1Oxidoreductases (Dehydrogenase)IBA
02/2016

Therapy/Procedure

29Therapeutics
11/2021 - 05/2002
20Drug Therapy (Chemotherapy)
10/2021 - 01/2003
5Radiotherapy
01/2019 - 01/2006
3Precision Medicine
11/2021 - 12/2019
3Craniospinal Irradiation
12/2016 - 06/2014
2Immunotherapy
01/2022 - 01/2021
2Aftercare (After-Treatment)
01/2019 - 05/2002
1Hematopoietic Stem Cell Transplantation
11/2021
1Transplantation
11/2021
1Lymph Node Excision (Lymph Node Dissection)
01/2021
1Transcutaneous Electric Nerve Stimulation (TENS)
06/2016